Background
Modulation of chromatin structure via histone modification plays an important role in the regulation of transcription in eukaryotes. Euchromatin, or loosely packed chromatin, is associated with gene expression, whereas tightly coiled chromatin, or heterochromatin, is associated with gene silencing. Previous research has shown that trimethylation of histone H3 on lysine 4, 36, and 79 is connected to gene activation.
Description
EpiGentek's Antibody Panel Packs provide a convenient way to investigate a panel of modifications using a collection of select antibodies. The Histone H3 Methylation Antibody Panel Pack II – Active Genes is a complete set of 4 vials for the investigation of active genes:
Product Name | Size | Applications | Reactivity |
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Histone H3K4me3 (H3K4 Trimethyl) Polyclonal Antibody | 25 µg | ChIP, ELISA, IF, IHC, IP, WB | Broad Range, Human, Mouse, Rat |
Histone H3K36me3 (H3K36 Trimethyl) Polyclonal Antibody | 25 µg | ChIP, ELISA, IF, IHC, IP, WB | Broad Range, Human, Mouse, Rat |
Histone H3K79me3 (H3K79 Trimethyl) Polyclonal Antibody | 25 µg | ChIP, ELISA, IF, IHC, IP, WB | Broad Range, Human, Mouse, Rat |
HRP-Goat Anti-Rabbit Secondary Antibody | 50 µg | ELISA, IF, IHC, WB | Rabbit |
Storage
Varies. Please see user guide for recommended storage conditions for each antibody.