Background
Modulation of chromatin structure via histone modification plays an important role in the regulation of transcription in eukaryotes. Euchromatin, or loosely packed chromatin, is associated with gene expression, whereas tightly coiled chromatin, or heterochromatin, is associated with gene silencing. Previous research has shown that asymmetric and symmetric dimethylation of histone H3 on arginine 2 and 8 is connected to gene repression.
Description
EpiGentek's Antibody Panel Packs provide a convenient way to investigate a panel of modifications using a collection of select antibodies. The Histone H3 Methylation Antibody Panel Pack II – Repression Genes is a complete set of 5 vials for the investigation of repression genes:
| Product Name | Size | Applications | Reactivity |
|---|
| Histone H3R2 Dimethyl Asymmetric (H3R2me2a) Polyclonal Antibody | 25 µg | ChIP, IF, IHC, IP, WB | Broad Range, Human, Mouse, Rat |
| Histone H3R2 Dimethyl Symmetric (H3R2me2s) Polyclonal Antibody | 25 µg | ChIP, IF, IHC, IP, WB | Broad Range, Human, Mouse, Rat |
| Histone H3R8 Dimethyl Asymmetric (H3R8me2a) Polyclonal Antibody | 25 µg | IF, IHC, WB | Broad Range, Human, Mouse, Rat |
| Histone H3R8 Dimethyl Symmetric (H3R8me2s) Polyclonal Antibody | 25 µg | ChIP, IF, IHC, IP, WB | Broad Range, Human, Mouse, Rat |
| HRP-Goat Anti-Rabbit Secondary Antibody | 50 µg | ELISA, IF, IHC, WB | Rabbit |
Storage
Varies. Please see user guide for recommended storage conditions for each antibody.
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